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Diagnostic Science Manager

Location Cambridge, England, United Kingdom Job ID R-229783 Date posted 22/06/2025
Job Title: Diagnostic Science Manager

Location: Cambridge, UK

Salary: Competitive + Excellent Employee Benefits!

Applications Deadline: July 07

Are you an experienced diagnostic scientist with a passion to apply your skills and bring technical expertise and scientific innovation to develop diagnostics for use in a clinical setting? If so, this could be the role for you!  

AstraZeneca delivers companion and complementary diagnostic assays that match medicines to those patients who are most likely to benefit from them. This approach, known as Precision Medicine, is based on those individual characteristics that make some patients respond to treatment better than others. We use this knowledge to develop diagnostic tests that doctors can use to help prescribe the best treatment for each patient. 

The role holder will be accountable for:

  • Being responsible for the delivery of laboratory based diagnostic assays with a particular focus on immunohistochemistry and histopathology, through close collaboration with cross-functional teams.

  • Delivering laboratory testing and research in our accredited laboratory.

  • Building and maintaining a knowledge of current and new technologies in diagnostics for the AZ oncology portfolio, and seeking opportunities for innovation and internal/external collaborations.

  • Developing innovative diagnostic science proposals across core therapeutic areas.

  • Ensuring that all activities are delivered demonstrating behaviours and values aligned to AstraZeneca Code of Conduct and supporting policies, standards and procedures, including compliant management of Budget, Safety, Health and Environment.

Education, Qualifications, Skills and Experience:

Essential:

  • Masters level or equivalent experience in a relevant subject.

  • Expertise with IHC and one or more of the following ISH, histopathology, digital pathology.

  • Experience developing and running tissue-based diagnostic assays in a regulated laboratory environment e.g. under In Vitro Diagnostics development standards, for example NHS laboratory, CAP/CLIA laboratory or diagnostic company.

  • Experience of working with external collaborators (for example academic investigators and/or diagnostic companies).

  • Ability to connect with cross-functional stakeholders for project updates through oral presentations and progress reports.

  • Record of delivery in a scientific capability, including peer-reviewed publications.

Desirable: 

  • Experience of multiplex protein technologies, NGS, PCR and emerging innovative diagnostic technologies.

  • Excellent knowledge of current technology trends in oncology diagnostics and precision medicine.

  • Good computational and data analysis skills enabling automated/semi-automated analysis of large datasets (e.g. using software and programming languages such as R, Python, knime or equivalent). 

  • Knowledge of requirements related to handling of Human Biological Samples.

Why AstraZeneca?

At AstraZeneca, we stand at the forefront of scientific innovation, passionately merging pioneering technology with groundbreaking research to redefine the boundaries of drug discovery and personalized healthcare. We nurture an environment where curiosity and courage propel us to tackle the biology of complex diseases without fear of failure, driving bold decisions and ambitious breakthroughs.

Our team thrives in an encouraging atmosphere, equipped with state-of-the-art resources that empower professionals to celebrate both their triumphs and setbacks. With us, you will not only impact the future of medicine but also enjoy competitive compensation, benefits, and robust career development opportunities. Join us on this exciting journey to make a meaningful impact in the world.

So, what’s next?

  • Are you ready to bring new insights and fresh thinking to the table? Brilliant! We have one seat available, and we hope it’s yours.

  • We encourage you to apply online before July 07.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

Date Posted

23-Jun-2025

Closing Date

06-Jul-2025

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. ]]>

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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Glassdoor logo Rated four stars on Glassdoor

Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value inclusion and diversity.